Indigenous peoples are fighting the COVID-19 pandemic daily, taking strong measures to protect their communities and territories from this virus. In these times, historical exclusions affecting rights to basic services and health infrastructure have become more acute, making indigenous peoples an extremely fragile and vulnerable section of society in this pandemic. In addition, attempts to appropriate traditional lands, territories and resources and open up areas for mining and commercial exploitation continue in certain regions. At the same time, indigenous peoples, through their indigenous knowledge and experience in natural resource stewardship, offer the wider world valuable insights, strategies and solutions for reducing the spread of COVID-19 and enhancing the resilience of communities and nature during the current crisis and beyond.