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In October, United Nations secretary-general António Guterres made a series of key appointments. He tasked 15 scientists from around the world with providing policymakers with evidence, as well as their thoughts, on the Sustainable Development Goals (SDGs). This time last year, the UN’s flagship plan to end poverty and guide the world to environmental sustainability by 2030 was already off track. Since then, the pandemic has reversed most of the achievements made in the five years since countries adopted the goals.